Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatitis C virus transmission bottlenecks analyzed by deep sequencing.

Journal of virology - 1 Jun 2010

Wang Gary P, Sherrill-Mix Scott A, Chang Kyong-Mi, Quince Chris, Bushman Frederic D

Abstract excerpt

Hepatitis C virus (HCV) replication in infected patients produces large and diverse viral populations, which give rise to drug-resistant and immune escape variants. Here, we analyzed HCV populations during transmission and diversification in longitudinal and cross-sectional samples using 454/Roche pyrosequencing, in total analyzing 174,185 sequence reads. To sample diversity, four locations in the HCV genome were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Genetic Variation
Share to Hepacivirus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C

Share to Hepatitis C virus research

Share to Molecular Sequence Data

Share to Phylogeny

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 20375170
DOI: 10.1128/JVI.02271-09
PMCID: PMC2876626

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepatitis C virus transmission bottlenecks analyzed by deep sequencing.PMID 20375170Read ↗

Sequential bottlenecks drive viral evolution in early acute hepatitis C virus infection.Semantic proximity Read ↗

Elucidation of Hepatitis C Virus Transmission and Early Diversification by Single Genome SequencingSemantic proximity Read ↗

Deep sequencing in the management of hepatitis virus infections.Semantic proximity Read ↗

Exceptional Heterogeneity in Viral Evolutionary Dynamics Characterises Chronic Hepatitis C Virus InfectionSemantic proximity Read ↗

High resolution evolutionary analysis of within-host hepatitis C virus infectionSemantic proximity Read ↗

Deep sequencing: becoming a critical tool in clinical virology.Semantic proximity Read ↗

High-Resolution Evolutionary Analysis of Within-Host Hepatitis C Virus Infection.Semantic proximity Read ↗

Rapid hepatitis C virus divergence among chronically infected individuals.Semantic proximity Read ↗

Hepatitis C virus molecular evolution: transmission, disease progression and antiviral therapy.Semantic proximity Read ↗

[Clinical impact of hepatitis C virus genomic variations].Semantic proximity Read ↗

Therapy Implications of Hepatitis C Virus Genetic Diversity.Semantic proximity Read ↗

Highly heterogeneous mutation rates in the hepatitis C virus genome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.