Article

Colorimetric LAMP assay for detection of the TP53 R337H single- nucleotide variant

2026-03-18

Abstract excerpt

<title>Abstract</title> <p> The human TP53 gene plays a central role in maintaining genomic stability, and germline variants in this gene are associated with hereditary cancer predisposition syndromes. The R337H single-nucleotide variant (SNV), highly prevalent in the Brazilian population, is an important genetic marker for cancer risk assessment and clinical surveillance. However, detection of SNVs usually requ...

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Literature Corpus work: f624094d-77c0-5d78-b7fe-5effd9aaa905
DOI: 10.21203/rs.3.rs-8934835/v1

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