Article
Establishment and application of a real-time loop-mediated isothermal amplification system for the detection of CYP2C19 polymorphisms.
Scientific reports - 1 Jun 2016
Zhang Chao, Yao Yao, Zhu Juan-Li, Zhang Si-Nong, Zhang Shan-Shan, Wei Hua, Hui Wen-Li, Cui Ya-Li
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) represent the most widespread type of genetic variation (approximately 90%) in the human genome, and the demand to overcome such variation has received more attention now than ever before. The capacity to rapidly assess SNPs that correlate with disease predisposition, drug efficacy and drug toxicity is a key step for the development of personalized medicine. In this work, a...
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