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Article

A direct isothermal amplification system adapted for rapid SNP genotyping of multifarious sample types.

Biosensors & bioelectronics - 15 Sept 2018

Liu Xiaonan, Zhang Chao, Zhao Mengye, Liu Kewu, Li Hang, Li Ningning, Gao Linlin, Yang Xuemin, Ma Ting, Zhu Juanli, Hui Wenli, Hua Kai, Cui Yali

Abstract excerpt

Genotyping of single nucleotide polymorphisms (SNPs) in point-of-care (POC) settings could be further improved through simplifying the treatment of samples. In this study, we devised an accurate, rapid and easy-to-use SNP detection system based on direct loop-mediated isothermal amplification (LAMP) without DNA extraction, known as Direct-LAMP. Samples from various sources (including whole blood, dried blood...

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Share to Aldehyde Dehydrogenase, Mitochondrial
Share to Biosensing Techniques

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ALDH2 gene

Share to Genotype

Share to Genotyping Techniques

Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 29803102
DOI: 10.1016/j.bios.2018.05.021
PMCID: PMC7126597

Genes

ALDH2
MTHFR

Variants

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