Article
Polymorphism genotyping based on loop-mediated isothermal amplification and smartphone detection.
Biosensors & bioelectronics - 30 Jun 2018
Yamanaka Eric Seiti, Tortajada-Genaro Luis A, Pastor Nuria, Maquieira Ángel
Abstract excerpt
The genotyping of a single-nucleotide polymorphism (SNP) is addressed through methods based on loop-mediated isothermal amplification (LAMP) combined with user-friendly optical read-outs to cover the current demand for point-of-care DNA biomarker detection. The modification of primer design and reaction composition improved the assay selectivity yielding allele-specific results and reducing false-positive...
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