Competitive SNP-LAMP probes for rapid and robust single-nucleotide polymorphism detection

Abstract excerpt

Single-nucleotide polymorphisms (SNPs) are the most common source of genetic variation between individuals and have implications in human disease, pathogen drug resistance, and agriculture. SNPs are typically detected using DNA sequencing, which requires advanced sample preparation and instrumentation, and thus cannot be deployed for on-site testing or in low-resource settings. In this work we have developed a sim...

Topics

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• COVID-19
• Fluorescent Dyes
• Mutation
• Nucleic Acid Amplification Techniques
• Point-of-Care Systems
• Polymorphism, Single Nucleotide
• Reproducibility of Results
• SARS-CoV-2

Identifiers and source

Literature Corpus work

67a7aaee-51f0-51ac-80c4-c217a3973331

DOI

10.1101/2021.03.29.437576