Article

Gene regulatory network determinants of rapid recall in human memory CD4+ T cells

2025-04-10

Abstract excerpt

Rapid recall is the hallmark of memory T cells. While naive cells require days to mount effector responses to new threats, antigen-experienced memory cells produce cytokines within hours of repeat encounter. Memory establishment and the control of rapid recall across lifespan is poorly understood. Epigenetic poising is a likely mechanism. Compared to naive, memory cells exhibit enhanced chromatin accessibility pro...

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Literature Corpus work: f5e63755-2b0b-55b0-b804-04f26fe22aa6
DOI: 10.1101/2025.04.06.646912

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