Article

A dynamic activation–memory cycle organizes the human IgG⁺ memory B cell compartment

2025-10-31

Abstract excerpt

B cells underpin durable immunity by generating long-lived memory B cells and antibody-secreting cells (ASCs) that re-engage upon antigen re-encounter. How human IgG⁺ memory B cells are organized to establish, maintain, and reactivate humoral immunity remains incompletely understood. Here, we combine multimodal single-cell profiling with longitudinal characterization of antigen-specific memory B cells following SA...

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Literature Corpus work: c01c08d4-e8cf-5557-927c-a8e20b3205a5
DOI: 10.1101/2025.10.30.685644

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