Article

Memory T cell rapid recall is driven by memory-specific AP-1 recruitment determined by epigenome and co-factor interactions

2026-02-16

Abstract excerpt

<h4>ABSTRACT</h4> CD4 T cell memory is essential for long-lasting protective immunity to repeat infections. Unlike naïve T cells, memory cells possess rapid recall ability to quickly produce effector molecules in response to antigen re-exposure. This ability was shown to be associated with epigenetic gene poising. Here, we examine how the activation-inducible transcription factors, AP□1 and NF□κB, regulate rapid...

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Literature Corpus work: e2d65bbe-f7be-5b30-8f13-d33f754afc0c
DOI: 10.64898/2026.02.13.705382

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