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Article

Runx proteins and transcriptional mechanisms that govern memory CD8 T cell development

1 Mar 2021

Abstract excerpt

Abstract Adaptive immunity to intracellular pathogens and tumors is mediated by antigen‐experienced CD8 T cells. Individual naive CD8 T cells have the potential to differentiate into a diverse array of antigen‐experienced subsets that exhibit distinct effector functions, life spans, anatomic positioning, and potential for regenerating an entirely new immune response during iterative pathogenic exposures. The...

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PMID: 33682165
DOI: 10.1111/imr.12954

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