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qBiCo: A method to assess global DNA conversion performance in epigenetics via single-copy genes and repetitive elements

2024-08-30

Abstract excerpt

Human DNA methylation profiling offers great promises in various biomedical applications, including ageing, cancer and even forensics. So far, most DNA methylation techniques are based on a chemical process called sodium bisulfite conversion, which specifically converts non-methylated cytosines into uracils. However, despite the popularity of this approach, it is known to cause DNA fragmentation and loss affecting...

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Literature Corpus work
f5da9ff0-ebb1-598b-905f-0e5b751378c8
DOI
10.1101/2024.08.29.610354
Open publication

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qBiCo: A method to assess global DNA conversion performance in epigenetics via single-copy genes and repetitive elementsDOI 10.1101/2024.08.29.610354
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