Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panels

22 Jun 2020

Abstract excerpt

BACKGROUND: DNA methylation is a well-studied epigenetic mark that is frequently altered in diseases such as cancer, where specific changes are known to reflect the type and severity of the disease. Therefore, there is a growing interest in assessing the clinical utility of DNA methylation as a biomarker for diagnosing disease and guiding treatment. The development of an accurate loci-specific methylation assay,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Genomics and Diagnostics
Share to Epigenetics and DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32571390
DOI: 10.1186/s13148-020-00880-y

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive evaluation of targeted multiplex bisulphite PCR sequencing for validation of DNA methylation biomarker panelsPMID 32571390Read ↗

Quantitative and multiplexed DNA methylation analysis using long-read single-molecule real-time bisulfite sequencing (SMRT-BS)Semantic proximity Read ↗

MethPanel: a parallel pipeline and interactive analysis tool for multiplex bisulphite PCR sequencing to assess DNA methylation biomarker panels for disease detectionSemantic proximity Read ↗

The BisPCR2 method for targeted bisulfite sequencingSemantic proximity Read ↗

Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation dataSemantic proximity Read ↗

SMAP: a streamlined methylation analysis pipeline for bisulfite sequencing.Semantic proximity Read ↗

Analyzing the cancer methylome through targeted bisulfite sequencing.Semantic proximity Read ↗

Comparing methylation levels assayed in GC-rich regions with current and emerging methodsSemantic proximity Read ↗

A streamlined method for analysing genome-wide DNA methylation patterns from low amounts of FFPE DNASemantic proximity Read ↗

Genome-scale DNA methylation analysis.Semantic proximity Read ↗

The implications of heterogeneous DNA methylation for the accurate quantification of methylation.Semantic proximity Read ↗

Bisulphite Sequencing of Chromatin Immunoprecipitated DNA (BisChIP-seq).Semantic proximity Read ↗

qBiCo: A method to assess global DNA conversion performance in epigenetics via single-copy genes and repetitive elementsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.