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Laboratory methods to decipher epigenetic signatures: a comparative review

11 Nov 2021

Abstract excerpt

Epigenetics refers to nucleotide sequence-independent events, and heritable changes, including DNA methylation and histone modification (as the two main processes), contributing to the phenotypic features of the cell. Both genetics and epigenetics contribute to determining the outcome of regulatory gene expression systems. Indeed, the flexibility of epigenetic effects and stability of genetic coding lead to gene...

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PMID: 34763654
DOI: 10.1186/s11658-021-00290-9

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