Article
In depth analysis of kinase cross screening data to identify chemical starting points for inhibition of the nek family of kinases
2017-05-14
Abstract excerpt
Potent, selective, and cell active small molecule kinase inhibitors are useful tools to help unravel the complexities of kinase signaling. As the biological functions of individual kinases become better understood, they can become targets of drug discovery efforts. The small molecules used to shed light on function can also then serve as chemical starting points in these drug discovery efforts. The Nek family of k...
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Identifiers and source
- Literature Corpus work
- f5be552c-c0f5-52f7-a5e7-f2cba38ee328
- DOI
- 10.1101/137968