Article

Progress Towards a Public Chemogenomic Set for Protein Kinases and a Call for Contributions

2017-01-31

Abstract excerpt

Protein kinases are highly tractable targets for drug discovery. However, the biological function and therapeutic potential of the majority of the 500+ human protein kinases remains unknown. We have developed physical and virtual collections of small molecule inhibitors, which we call chemogenomic sets, that are designed to inhibit the catalytic function of almost half the human protein kinases. In this manuscript...

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Literature Corpus work: dd26f7f0-8d9e-539f-9ecb-2f639ec612bf
DOI: 10.1101/104711

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