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Article

The kinome 'at large' in cancer.

Nature reviews. Cancer - 1 Feb 2016

Fleuren Emmy D G, Zhang Luxi, Wu Jianmin, Daly Roger J

Abstract excerpt

Over the past decade, rapid advances in genomics, proteomics and functional genomics technologies that enable in-depth interrogation of cancer genomes and proteomes and high-throughput analysis of gene function have enabled characterization of the kinome 'at large' in human cancers, providing crucial insights into how members of the protein kinase superfamily are dysregulated in malignancy, the context-dependent...

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PMID: 26822576
DOI: 10.1038/nrc.2015.18

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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