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A resource for exploring the understudied human kinome for research and therapeutic opportunities

2020-04-02

Abstract excerpt

<h4>ABSTRACT</h4> The functions of protein kinases have been widely studied and over 60 kinase inhibitors are FDA-approved drugs. Membership in the human kinome is nonetheless subject to multiple overlapping and inconsistent definitions and is unevenly studied, complicating functional genomics and chemical genetics. We describe objective criteria for refining the definition of the human kinome to comprise an exte...

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Literature Corpus work
da63b02b-0d1b-5e82-bf40-532ff67036cd
DOI
10.1101/2020.04.02.022277
Open publication

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A resource for exploring the understudied human kinome for research and therapeutic opportunitiesDOI 10.1101/2020.04.02.022277
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