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Article

Causal Effect of Multicohort Circulating Proteome on the Risk of Aortic Aneurysm: A Mendelian Randomization Study.

Annals of vascular surgery - 1 Aug 2026

Ding Meizhu, Li Yinggao, Yao Shasha, Wang Kan

Abstract excerpt

BACKGROUND: The pathogenesis of aortic aneurysm (AA) remains unclear, and there are no effective therapeutic drugs or targets. Circulating plasma proteins are considered biomarkers of AA and potential therapeutic targets for AA. This study aimed to systematically evaluate the causal effects of plasma proteins on AA using a multicohort Mendelian randomization (MR) approach. METHODS: Protein quantitative trait loci...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41895592
DOI: 10.1016/j.avsg.2026.03.008

Genes

AHSG
CCL25
HPSE
LPA
MMP7
OVCA2
PLAU
RARRES2
SERPING1
SMPDL3A
STAT3
THBS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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