Article

Identifying Circulating Protein Mediators in the Link Between Smoking and Abdominal Aortic Aneurysm: An Integrated Analysis of Human Proteomic and Genomic Data

2025-03-01

Abstract excerpt

<h4>Background</h4> Smoking is a well-established risk factor for abdominal aortic aneurysm (AAA). However, the molecular pathways underlying this relationship remain poorly understood. This study aimed to identify circulating protein mediators that may explain the association between smoking and AAA. <h4>Methods</h4> We conducted a network Mendelian randomization (MR) study utilizing summary-level data from the l...

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Literature Corpus work: ee3b246e-9855-53f3-84d5-66d6d3f9c5d7
DOI: 10.1101/2025.02.27.25322973

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