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Article

Genetic associations of circulating plasma proteins with cardiometabolic diseases.

Genome biology - 28 Jan 2026

Zhou Ruixin, Qiao Jun, Zhang Xiuzhen, Yang Xiaofei, Hong Wanzi, Cai Liuyang, Zhang Pengwei, Pauklin Siim, Yang Yining, Xu Zhaoyan, Feng Yuliang

Abstract excerpt

BACKGROUND: Cardiovascular disease is the leading cause of death worldwide, and its risk is closely linked to metabolic abnormalities. Through summary-data-based mendelian randomization and colocalization analysis, we investigate the causal relationships between plasma proteins, six cardiovascular diseases (atrial fibrillation, coronary artery disease, heart failure, venous thromboembolism, peripheral artery...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41606682
DOI: 10.1186/s13059-026-03962-x
PMCID: PMC12924215

Genes

APOH
DUSP13B
INHBC
GUSB
PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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