Article

Causal Effect of Multi-cohort Circulating Proteome on the Risk of Aortic Aneurysm: A Mendelian Randomization Study

2024-11-17

Abstract excerpt

<h4>Background</h4> The pathogenesis of aortic aneurysm (AA) remains unclear, and there are no effective therapeutic drugs or targets. Circulating plasma proteins are considered biomarkers of AA and potential therapeutic targets for AA. This study aimed to systematically evaluate the causal effects of plasma proteins on AA using a multi-cohort Mendelian randomization (MR) approach. <h4>Methods</h4> Protein quantit...

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Literature Corpus work: f4979e82-4e59-5ce9-8e3b-2ba14b4e91a7
DOI: 10.1101/2024.11.17.24317384

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