Article

RFX4 maintains excitatory–inhibitory balance through WNT-dependent cortical patterning: implications for neurodevelopmental disorders

2026-08-06

Abstract excerpt

<title>Abstract</title> Human cortical development depends on tightly regulated transcriptional and signaling networks, while their disruption can lead to neurodevelopmental disorders. Meanwhile, the roles of key transcription factors in human-specific cortical patterning remain incompletely understood. Aberrant function of regulatory factor X4 (RFX4) has been implicated in diverse neurodevelopmental and neuro...

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Literature Corpus work: f563ccf8-a95e-59d4-8a92-ec2910166017
DOI: 10.21203/rs.3.rs-10383824/v1

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