Back to search

Article

Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate

2025-09-24

Abstract excerpt

Human cortical neurogenesis involves conserved and specialized developmental processes during a restricted window of prenatal development. Radial glia (RG) neural stem cells shape cortical cell diversity by giving rise to excitatory neurons, oligodendrocytes, and astrocytes, as well as olfactory bulb interneurons (INs) and a recently characterized population of cortical INs 1,2 . Complex genetic programs orchestr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
229036a1-0644-5a4c-8ea4-16f7571419c1
DOI
10.1101/2025.09.23.678137
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Dissecting Gene Regulatory Networks Governing Human Cortical Cell FateDOI 10.1101/2025.09.23.678137
Cell-type-specific 3D epigenomes in the developing human cortex.Semantic proximity
3D Epigenomic Characterization Reveals Insights Into Gene Regulation and Lineage Specification During CorticogenesisSemantic proximity
Early Developmental Origins of Cortical Disorders Modeled in Human Neural Stem CellsSemantic proximity
Massively parallel disruption of enhancers active during human corticogenesisSemantic proximity
A single cell transcriptomic analysis of human neocortical developmentSemantic proximity
Human Accelerated Regions regulate gene networks implicated in apical-to-basal neural progenitor fate transitionsSemantic proximity
<i>NEUROG2</i> regulates a human-specific neurodevelopmental gene regulatory programSemantic proximity
An Atlas of Cortical Arealization Identifies Dynamic Molecular SignaturesSemantic proximity
Inferring and perturbing cell fate regulomes in human cerebral organoidsSemantic proximity
Comparative single-cell regulome reveals evolutionary innovations in neural progenitor cells during primate corticogenesisSemantic proximity
Intellectual disability risk gene RFX4 regulates cortical neurogenesis by restraining neuronal differentiationSemantic proximity
Reprogramming of neuronal genome function and phenotype by astrocytesSemantic proximity
Select a neighboring publication to make it the new centre.