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Article

Genetic dissection of the obesity paradox in carotid atherosclerosis using a hyperlipidemic mouse cohort

2026-08-18

Abstract excerpt

<h4>Background</h4> Overweight and obese individuals often exhibit lower mortality rates or better prognoses than lean or normal-weight individuals with stroke and other diseases, a phenomenon called the “obesity paradox”. Carotid atherosclerosis is the primary cause of ischemic stroke, and body weight serves as a reliable surrogate for adiposity in mice. <h4>Methods</h4> Phenotypic and genetic connections of ca...

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Literature Corpus work
f5580dcc-d5fb-5b3f-8858-db711ec7caff
DOI
10.64898/2026.08.13.744610
Open publication

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Genetic dissection of the obesity paradox in carotid atherosclerosis using a hyperlipidemic mouse cohortDOI 10.64898/2026.08.13.744610
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