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Article

Atherosclerosis susceptibility Loci identified in an extremely atherosclerosis-resistant mouse strain.

Journal of the American Heart Association - 12 Aug 2013

Rowlan Jessica S, Li Qiongzhen, Manichaikul Ani, Wang Qian, Matsumoto Alan H, Shi Weibin

Abstract excerpt

BACKGROUND: C3H/HeJ (C3H) mice are extremely resistant to atherosclerosis, especially males. To understand the underlying genetic basis, we performed quantitative trait locus (QTL) analysis on a male F2 (the second generation from an intercross between 2 inbred strains) cohort derived from an intercross between C3H and C57BL/6 (B6) apolipoprotein E-deficient (Apoe(-/-)) mice. METHODS AND RESULTS: Two hundred...

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Identifiers

PMID: 23938286
DOI: 10.1161/JAHA.113.000260
PMCID: PMC3828785

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Source receipt: pubmed, retrieved 7 Sept 2026.

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