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Article

Regional Variation in Genetic Control of Atherosclerosis in Hyperlipidemic Mice.

G3 (Bethesda, Md.) - 3 Dec 2020

Jones Michael B, An Alexander, Shi Lisa J, Shi Weibin

Abstract excerpt

Atherosclerosis is a polygenic disorder that often affects multiple arteries. Carotid arteries are common sites for evaluating subclinical atherosclerosis, and aortic root is the standard site for quantifying atherosclerosis in mice. We compared genetic control of atherosclerosis between the two sites in the same cohort derived from two phenotypically divergent Apoe-null (Apoe-/-) mouse strains. Female F2 mice...

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Identifiers

PMID: 33109727
DOI: 10.1534/g3.120.401856
PMCID: PMC7718748

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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