Article
Polygenic Control of Carotid Atherosclerosis in a BALB/cJ × SM/J Intercross and a Combined Cross Involving Multiple Mouse Strains.
G3 (Bethesda, Md.) - 9 Feb 2017
Grainger Andrew T, Jones Michael B, Chen Mei-Hua, Shi Weibin
Abstract excerpt
Atherosclerosis in the carotid arteries is a major cause of ischemic stroke, which accounts for 85% of all stroke cases. Genetic factors contributing to carotid atherosclerosis remain poorly understood. The aim of this study was to identify chromosomal regions harboring genes contributing to carotid atherosclerosis in mice. From an intercross between BALB/cJ (BALB) and SM/J (SM) apolipoprotein E-deficient...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
