Article
Candidate genes for obesity revealed from a C57BL/6J x 129S1/SvImJ intercross.
International journal of obesity (2005) - 1 Jul 2008
Su Z, Korstanje R, Tsaih S-W, Paigen B
Abstract excerpt
OBJECTIVE: To identify the genes controlling body fat, we carried out a quantitative trait locus (QTL) analysis using C57BL/6J (B6) and 129S1/SvImJ (129) mice, which differ in obesity susceptibility after consuming an atherogenic diet. METHODS: Mice were fed chow until 8 weeks and an atherogenic diet from 8 to 16 weeks; body fatness was measured by X-ray absorptiometry in 528 (B6 x 129) F(2) at 8 and 16 weeks. A...
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