Article
Genetic-genomic replication to identify candidate mouse atherosclerosis modifier genes.
Journal of the American Heart Association - 23 Jan 2013
Hsu Jeffrey, Smith Jonathan D
Abstract excerpt
OBJECTIVE: Genetics plays a large role in atherosclerosis susceptibility in humans and mice. We attempted to confirm previously determined mouse atherosclerosis-associated loci and use bioinformatics and transcriptomics to create a catalog of candidate atherosclerosis modifier genes at these loci. METHODS AND RESULTS: A strain intercross was performed between AKR and DBA/2 mice on the apoE(-/-) background...
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