Genetic insights into therapeutic targets for aortic aneurysms: A Mendelian randomization study

Abstract excerpt

BACKGROUND: As aortic aneurysms (AAs) enlarge, they can become life-threatening if left undiagnosed or neglected. At present, there is a lack of radical treatments for preventing disease progression. Therefore, we aimed to identify effective drug targets that slow the progression of AAs. METHODS: A Mendelian randomization (MR) analysis was conducted to identify therapeutic targets which are associated with AAs....

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