Article

A multi-omic integrative scheme characterizes tissues of action at loci associated with type 2 diabetes

2020-06-25

Abstract excerpt

Resolving the molecular processes that mediate genetic risk remains a challenge as most disease-associated variants are non-coding and functional and bioinformatic characterization of these signals requires knowledge of the specific tissues and cell-types in which they operate. To address this challenge, we developed a framework for integrating tissue-specific gene expression and epigenomic maps (primarily from ti...

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Literature Corpus work: f42858c5-7ed2-5137-8b89-0308da2d65d3
DOI: 10.1101/2020.06.25.169706

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