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Article

High-Resolution Genetic Maps Identify Multiple Type 2 Diabetes Loci at Regulatory Hotspots in African Americans and Europeans.

American journal of human genetics - 4 May 2017

Lau Winston, Andrew Toby, Maniatis Nikolas

Abstract excerpt

Interpretation of results from genome-wide association studies for T2D is challenging. Only very few loci have been replicated in African ancestry populations and the identification of the implicated functional genes remain largely undefined. We used genetic maps that capture detailed linkage disequilibrium information in European and African Americans and applied these to large T2D case-control samples in order...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28475862
DOI: 10.1016/j.ajhg.2017.04.007
PMCID: PMC5420350

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