Article

Symmetry breaking of hPSCs in micropattern generates a polarized spinal cord-like organoid (pSCO) with dorsoventral organization

2021-09-19

Abstract excerpt

Brain organoid research is advancing, but generation of organoids with proper axis formation, which could lead to spatially ordered structures for complex brain structure and function, still remains a challenge. Axis formation and related spatial cell organization in the CNS are initiated by the symmetry breaking during the early embryo development. It has been demonstrated that the geometrically confined culture...

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Literature Corpus work: f3fb8b84-1396-5c4f-9e77-1122092b4bcb
DOI: 10.1101/2021.09.18.460734

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Symmetry breaking of hPSCs in micropattern generates a polarized spinal cord-like organoid (pSCO) with dorsoventral organizationDOI 10.1101/2021.09.18.460734Read

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