Article
Actuation Enhances Patterning in Human Neural Tube Organoids
2020-09-22
Abstract excerpt
Tissues achieve their complex spatial organization through an interplay between gene regulatory networks, cell-cell communication, and physical interactions mediated by mechanical forces. Current strategies to generate in-vitro tissues have largely failed to implement such active, dynamically coordinated mechanical manipulations, relying instead on extracellular matrices which respond to, rather than impose mechan...
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Identifiers and source
- Literature Corpus work
- dd0b06c3-afe8-5e80-8d92-82f2db721442
- DOI
- 10.1101/2020.09.22.308411