Article

Engineering Human CNS Morphogenesis: Controlled Induction of Singular Neural Rosette Emergence

2017-12-05

Abstract excerpt

Human pluripotent stem cell (hPSC)-derived neural organoids have revolutionized in vitro modelling of human neurological disorders. Cell-intrinsic morphogenesis processes displayed within these tissues could serve as the basis for ex vivo manufacture of brain and spinal cord tissues with biomimetic anatomy and physiology. However, we must first understand how to control their emergent properties starting at the ge...

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Literature Corpus work: da5c5bbc-0bef-56cd-9330-600d6552b558
DOI: 10.1101/229328

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