Article

Fine-mapping identifies 27 allele-specific MPRA regulatory variants in Parkinson’s disease related loci

2023-10-05

Abstract excerpt

<title>Abstract</title> <p>Genome wide association studies (GWAS) have identified a number of genomic loci that are associated with Parkinson’s disease (PD) risk. However, the majority of these variants lie in non-coding regions, and thus the mechanisms by which they influence disease development, and/or potential subtypes, remain largely elusive. To address this, we used a massively parallel reporter assay (MPRA...

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Literature Corpus work: f3c21cbc-1cc7-53a6-9c9e-7601aaa81c8e
DOI: 10.21203/rs.3.rs-3371418/v1

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