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Article

Functional genomics elucidates regulatory mechanisms of Parkinson's disease-associated variants.

BMC medicine - 16 Feb 2022

Chen Rui, Liu Jiewei, Li Shiwu, Li Xiaoyan, Huo Yongxia, Yao Yong-Gang, Xiao Xiao, Li Ming, Luo Xiong-Jian

Abstract excerpt

BACKGROUND: Genome-wide association studies (GWASs) have identified multiple risk loci for Parkinson's disease (PD). However, identifying the functional (or potential causal) variants in the reported risk loci and elucidating their roles in PD pathogenesis remain major challenges. To identify the potential causal (or functional) variants in the reported PD risk loci and to elucidate their regulatory mechanisms,...

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Identifiers

PMID: 35168626
DOI: 10.1186/s12916-022-02264-w
PMCID: PMC8848643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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