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Article

Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson's disease etiology.

Scientific reports - 27 Jul 2016

Coetzee Simon G, Pierce Steven, Brundin Patrik, Brundin Lena, Hazelett Dennis J, Coetzee Gerhard A

Abstract excerpt

Recent genome-wide association studies (GWAS) of Parkinson's disease (PD) revealed at least 26 risk loci, with associated single nucleotide polymorphisms (SNPs) located in non-coding DNA having unknown functions in risk. In order to explore in which cell types these SNPs (and their correlated surrogates at r(2) ≥ 0.8) could alter cellular function, we assessed their location overlap with histone modification...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

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Source

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Identifiers

PMID: 27461410
DOI: 10.1038/srep30509
PMCID: PMC4962314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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