Article
Missing heritability in Parkinson's disease: the emerging role of non-coding genetic variation.
Journal of neural transmission (Vienna, Austria : 1996) - 1 May 2020
Ohnmacht Jochen, May Patrick, Sinkkonen Lasse, Krüger Rejko
Abstract excerpt
Parkinson's disease (PD) is a neurodegenerative disorder caused by a complex interplay of genetic and environmental factors. For the stratification of PD patients and the development of advanced clinical trials, including causative treatments, a better understanding of the underlying genetic architecture of PD is required. Despite substantial efforts, genome-wide association studies have not been able to explain...
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