Article

CTLA4 protects against maladaptive cytotoxicity during differentiation of effector and follicular CD4+ T cells

2023-01-03

Abstract excerpt

<title>Abstract</title> <p>As chronic antigenic stimulation from infection and autoimmunity are features of primary antibody deficiency (PAD), analysis of affected patients could yield insights into T cell differentiation, and explain how environmental exposures modify clinical phenotypes conferred by single gene defects. CD57 marks dysfunctional T cells that have differentiated after antigenic stimulation. Indee...

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Literature Corpus work: f3b23f54-3ec8-5385-95f2-6c79c4fb2f6f
DOI: 10.21203/rs.3.rs-2377516/v1

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