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Article

Follicular helper T cell signature of replicative exhaustion, apoptosis and senescence in common variable immunodeficiency

2021-06-15

Abstract excerpt

<h4>Background</h4> Common variable immunodeficiency (CVID) is the most frequent primary antibody deficiency. A significant number of CVID patients are affected by various manifestations of immune dysregulation such as autoimmunity. Follicular T cells cells are thought to support the development of CVID by providing inappropriate signals to B cells during the germinal center (GC) response. <h4>Objectives</h4> We...

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Literature Corpus work
d4dc6776-642c-5ee1-b1d4-b84089157d47
DOI
10.1101/2021.06.15.448353
Open publication

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Follicular helper T cell signature of replicative exhaustion, apoptosis and senescence in common variable immunodeficiencyDOI 10.1101/2021.06.15.448353
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