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Article

CD4+ Cytotoxic T cells - Phenotype, Function and Transcriptional Networks Controlling Their Differentiation Pathways.

Immunology letters - 1 Jul 2022

Preglej Teresa, Ellmeier Wilfried

Abstract excerpt

The two major subsets of peripheral T cells are classically divided into the CD4+ T helper cells and the cytotoxic CD8+ T cell lineage. However, the appearance of some effector CD4+ T cell populations displaying cytotoxic activity, in particular during viral infections, has been observed, thus breaking the functional dichotomy of CD4+ and CD8+ T lymphocytes. The strong association of the appearance of CD4+...

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Identifiers

PMID: 35568324
DOI: 10.1016/j.imlet.2022.05.001

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