Article

A unified atlas of CD8 T cell dysfunctional states in cancer and infection

2020-07-26

Abstract excerpt

<h4>ABSTRACT</h4> CD8 T cells play an essential role in defense against viral and bacterial infections and in tumor immunity. Deciphering T cell loss of functionality is complicated by the conspicuous heterogeneity of CD8 T cell states described across different experimental and clinical settings. By carrying out a unified analysis of over 300 ATAC-seq and RNA-seq experiments from twelve independent studies of CD...

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Literature Corpus work: 115e1cc1-4aa2-570e-a7be-4e805a1c3237
DOI: 10.1101/2020.07.25.220673

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