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T cells in health and disease

18 Jun 2023

Abstract excerpt

Abstract T cells are crucial for immune functions to maintain health and prevent disease. T cell development occurs in a stepwise process in the thymus and mainly generates CD4 + and CD8 + T cell subsets. Upon antigen stimulation, naïve T cells differentiate into CD4 + helper and CD8 + cytotoxic effector and memory cells, mediating direct killing, diverse immune regulatory function, and long-term protection. In...

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PMID: 37332039
DOI: 10.1038/s41392-023-01471-y

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