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Article

The spatial landscape of clonal somatic mutations in benign and malignant tissue

2021-07-30

Abstract excerpt

<title>Abstract</title> <p>Defining the transition from benign to malignant tissue is fundamental to improve early diagnosis of cancer. Here, we provide an unsupervised approach to study spatial genome integrity in situ to describe previously unidentified clonal relationships. We employed spatially resolved transcriptomics to infer spatial copy number variations in >120 000 regions across multiple organs, in beni...

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Literature Corpus work
f3a667c3-3dda-5468-9ba9-935846e5d7e0
DOI
10.21203/rs.3.rs-745238/v1
Open publication

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The spatial landscape of clonal somatic mutations in benign and malignant tissueDOI 10.21203/rs.3.rs-745238/v1
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