Article

Scalable spatial DNA sequencing from archival tissue maps copy number subclones

2026-08-27

Abstract excerpt

Spatially resolved DNA sequencing holds promise due to its potential utility in understanding cancer intra-tumour heterogeneity and tumour evolution in relation to tissue architecture. However, it has so far been used to a limited extent due to technical challenges and high cost of existing methods. Hence we aimed to develop a high throughput spatial genomic assay to obtain copy number alteration (CNA) information...

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Literature Corpus work: 865f00c2-18d3-50b7-8530-076b35185ae6
DOI: 10.64898/2026.08.24.746226

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