Back to search

Article

Spatially resolved single-cell analysis uncovers protein kinase Cδ-expressing microglia with anti-tumor activity in glioblastoma

2023-12-05

Abstract excerpt

Glioblastoma (GBM) is a brain tumor that poses a formidable challenge to treatment options available. The tumor microenvironment (TME) in GBM is highly complex, marked by immunosuppression and cellular heterogeneity. Understanding the cellular interactions and their spatial organization within the TME is crucial for developing effective therapeutic strategies. In this study, we integrated single-cell RNA sequencin...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
f397fcd7-6c4a-5990-8726-a46847e1028d
DOI
10.1101/2023.12.04.570023
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Spatially resolved single-cell analysis uncovers protein kinase Cδ-expressing microglia with anti-tumor activity in glioblastomaDOI 10.1101/2023.12.04.570023
Select a neighboring publication to make it the new centre.