Article

Functional profiling of murine glioma models highlights targetable immune evasion phenotypes

2024-10-15

Abstract excerpt

<title>Abstract</title> <p>Cancer intrinsic immune evasion mechanisms and pleiotropy represent a barrier to effective translation of cancer immunotherapy. This is acutely apparent for certain highly fatal cancers such as high-grade gliomas and glioblastomas. In this study, we use functional genetic screens, single-cell transcriptomics and machine-learning approaches to deeply characterize murine syngeneic glioma...

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Literature Corpus work: 08d0525b-4b70-57ae-ae05-e02a5dd8a52d
DOI: 10.21203/rs.3.rs-4946878/v1

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