Article

Cell type-specific proteogenomic signal diffusion for integrating multi-omics data predicts novel schizophrenia risk genes

2020-05-30

Abstract excerpt

Accumulation of diverse types of omics data on schizophrenia (SCZ) requires a systems approach to jointly modeling the interplay between genome, transcriptome and proteome. Proteome dynamics, as the definitive cellular machinery in human body, has been lagging behind the research on genome/transcriptome in the context of SCZ, both at tissue and single-cell resolution. We introduce a Markov Affinity-based Proteogen...

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Literature Corpus work: f353e33d-9375-559b-885d-cd53856be7c0
DOI: 10.1101/2020.05.28.121517

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