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Transcriptomics and proteomics of projection neurons in a circuit linking hippocampus with dorsolateral prefrontal cortex in the human brain

2024-06-13

Abstract excerpt

Transcriptome and proteome sequencing of brain tissue homogenate has helped unravel processes underlying schizophrenia (SCZ). However, most studies have lacked granularity at the cell type level and have focused on individual brain regions, rather than examining expression dynamics across multiple regions or illness-relevant circuitries. We used laser capture microdissection to collect excitatory neuron-enriched s...

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Literature Corpus work
6a336bbb-d32d-5926-9153-8a6137bca5fb
DOI
10.1101/2024.06.12.598714
Open publication

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Transcriptomics and proteomics of projection neurons in a circuit linking hippocampus with dorsolateral prefrontal cortex in the human brainDOI 10.1101/2024.06.12.598714
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